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KMID : 1207720150070020254
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Clinics in Orthopedic Surgery
2015 Volume.7 No. 2 p.254 ~ p.260
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Distinct Clinical Characteristics of Unplanned Excision in Synovial Sarcoma
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Choi Eun-Seok
Han Il-Kyu
Cho Hwan-Seong
Kang Hyun-Guy
Kim June-Hyuk
Kim Han-Soo
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Abstract
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Background: We aimed to describe the clinical characteristics and outcomes of unplanned excisions of synovial sarcomas.
Methods: In total, 90 patients with synovial sarcomas in the extremities were retrospectively reviewed. Patients were divided into unplanned excision (n = 38) and planned excision (n = 52) groups. The average follow-up period was 6 years. The clinicopathological characteristics and oncologic outcomes were compared.
Results: The unplanned excision group showed longer duration of symptoms before diagnosis (p = 0.023), smaller lesion dimensions (p = 0.001), superficial location (p = 0.049), and predilection in the upper extremities (p = 0.037). Synovial sarcomas were most commonly misdiagnosed as neurogenic tumors (56%) in the upper extremities or as cystic masses (47%) in the lower extremities. Oncological outcomes, including disease-specific survival, metastasis-free survival, or local recurrence were not significantly different between the 2 groups (p = 0.159, p = 0.444, and p = 0.335, respectively). Repeated unplanned excision (p = 0.012) and delayed re-excision (p = 0.038) were significant risk factors for local recurrence in the unplanned excision group.
Conclusions: Synovial sarcomas treated with unplanned excision had distinct characteristics. These findings are important for developing diagnostic and therapeutic strategies for synovial sarcoma.
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KEYWORD
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Synovial sarcoma, Oncologic outcomes, Magnetic resonance imaging
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